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HEALTH ENCYCLOPEDIA

Diseases & Conditions A - Z
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Cancers

CANCER IN DEVELOPING COUNTRIES

Cancer trends are of great concern to the public health community. As developing countries become more industrialized, incidence and mortality rates for cancers of the breast, colon, rectum, and prostate begin to rise. Also, smoking is increasing worldwide—along with lung cancer incidence and mortality rates. Liver cancer shows the same trends as lung cancer, but for a different reason. Infection with the hepatitis B or C viruses is a major risk factor for liver cancer. In some countries, where a vaccine for hepatitis B is widely used to vaccinate infants, liver cancer incidence in later life has declined; however, incidence rates in developing countries, where vaccination is not widely available, appear to be increasing. Another virus, the human papillomavirus (HPV), is an important risk factor for cervical cancer. Cervical cancer and HPV are more common in equatorial countries (e.g., in Latin America, sub-Saharan Africa, and Southeast Asia) and less common in countries in northern latitudes. Screening and treatment for early stages of cervical cancer have made significant inroads for reducing the incidence and mortality of this disease.

HOWARD L. PARNES

DARRELL ANDERSON

(SEE ALSO: Breast Cancer; Carcinogen; Cervical Cancer; Colorectal Cancer; Environmental Determinants of Health; Environmental Tobacco Smoke; Genetics and Health; Geography of Disease; Geriatrics; Incidence and Prevalence; Lung Cancer; Melanoma; Mortality Rates; Nutrition; Occupational Safety and Health; Oral Cancer; Ovarian Cancer; Prevention; Preventive Health Behavior; Prostate Cancer; Screening; Skin Cancer)

BIBLIOGRAPHY

Doll, R., and Peto, R. (1981). "The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today." Journal of the National Cancer Institute 66:1191–1308.

Fleming, I. D.; Cooper, J. S.; Henson, D. E.; Hutter, >R. V. P.; Kennedy, B. J.; Murphy, G. P.; Sullivan, B. O.; Sobin, L. H.; and Yarbro, J. W. (1997). AJCC Cancer Staging Manual, 5th edition. New York: Lippincott Williams & Wilkins.

Greenlee, R. T. (2000). "Cancer Statistics, 2000." CA: A Cancer Journal for Clinicians 50:7–33.

Greenwald, P.; Kramer, B. S.; and Weed, D., eds. (1995). Cancer Prevention and Control. New York: Marcel Dekker.

Lichtenstein, P.; Holm, N. V.; Verkasalo, P. K.; Iliadou, A.; Kaprio, J.; Koskenvuo, M.; Pukkala, E.; Skytthe, A.; and Hemminki, K. (2000). "Environmental and Heritable Factors in the Causation of Cancer— Analyses of Cohorts of Twins from Sweden, Denmark, and Finland." New England Journal of Medicine 343(2):78–85.

Parkin, D. M.; Pisani, P.; and Ferlay, J. (1999). "Global Cancer Statistics." CA Cancer J Clin 49(1):33–64.

—— (1999). "Estimates of the Worldwide Incidence of 25 Major Cancers in 1990." International Journal of Cancer 80(6):827–841.

Pickle, L. W.; Mugiole, M.; Jones, G. K.; and White, A. A. (1996). Atlas of United States Mortality. Hyattsville, MD: U.S. Department of Health and Human Services (DHHS Publication No. [PHS] 97–1015).

Pisani, P.; Parkin, D. M.; Bray, F.; and Ferlay, J. (1999). "Estimates of the Worldwide Mortality from 25 Cancers in 1990." International Journal of Cancer 83(1):18–29.

Schottenfeld, D., and Fraumeni, J. F., Jr., eds. (1996). >Cancer Epidemiology and Prevention, 2nd edition. New York: Oxford University Press.

"What You Need to Know About Cancer." Scientific American 275(Spec. Issue, September 1996).

World Cancer Research Fund (1997). Food, Nutrition and the Prevention of Cancer: A Global Perspective. Washington, DC: American Institute for Cancer Research.

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Author Info: HOWARD L. PARNES, DARRELL ANDERSON, The Gale Group Inc., Macmillan Reference USA, New York, Gale Encyclopedia of Public Health, 2002

This feature is for informational purposes only and should not be used to replace the care and information received from your healthcare provider. Please consult a healthcare professional with any health concerns you may have.
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