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Generic Name: donepezil

It is used to treat mild to moderate dementia caused by Alzheimer's disease.
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What is this medicine?

DONEPEZIL (doe NEP e zil) is used to treat mild to moderate dementia caused by Alzheimer's disease.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • asthma or other lung disease
  • difficulty passing urine
  • head injury
  • heart disease, slow heartbeat
  • liver disease
  • Parkinson's disease
  • seizures (convulsions)
  • stomach or intestinal disease, ulcers or stomach bleeding
  • an unusual or allergic reaction to donepezil, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You may take this medicine with or without food. Take this medicine at regular intervals. This medicine is usually taken before bedtime. Do not take it more often than directed. Continue to take your medicine even if you feel better. Do not stop taking except on your doctor's advice.

If you are taking the 23 mg donepezil tablet, swallow it whole; do not cut, crush, or chew it.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose, do not take double or extra doses.

What may interact with this medicine?

  • atropine
  • benztropine
  • bethanechol
  • carbamazepine
  • dexamethasone
  • dicyclomine
  • glycopyrrolate
  • hyoscyamine
  • ipratropium
  • itraconazole or ketoconazole
  • medicines for motion sickness
  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
  • other medicines for Alzheimer's disease
  • oxybutynin
  • phenobarbital
  • phenytoin
  • quinidine
  • rifampin, rifabutin or rifapentine
  • trihexyphenidyl

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. Check with your doctor or health care professional if your symptoms do not get better or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • changes in vision
  • feeling faint or lightheaded, falls
  • problems with balance
  • slow heartbeat, or palpitations
  • stomach pain
  • unusual bleeding or bruising, red or purple spots on the skin
  • vomiting
  • weight loss

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea, especially when starting treatment
  • headache
  • indigestion or heartburn
  • loss of appetite
  • muscle cramps
  • nausea

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.
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Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.
 
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