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Generic Name: glimepiride

A sulfonylurea - Treatment is combined with diet and exercise

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What is this medicine?

GLIMEPIRIDE (GLYE me pye ride) helps to treat type 2 diabetes. Treatment is combined with diet and exercise. This medicine helps your body use insulin better.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

diabetic ketoacidosis
glucose-6-phosphate dehydrogenase deficiency
heart disease
kidney disease
liver disease
severe infection or injury
thyroid disease
an unusual or allergic reaction to glimepiride, sulfa drugs, other medicines, foods, dyes, or preservatives
pregnancy or recent attempts to get pregnant
breast-feeding

How should I use this medicine?

Take this medicine by mouth. Swallow with a drink of water. Follow the directions on the prescription label. Take your dose at the same time each day, with breakfast or your first large meal. Do not take more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Elderly patients over 65 years old can have a stronger reaction and need a smaller dose.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

bosentan
chloramphenicol
cisapride
clarithromycin
medicines for fungal or yeast infections
metoclopramide
probenecid
warfarin

Many medications may cause an increase or decrease in blood sugar, these include:

alcohol containing beverages
aspirin and aspirin-like drugs
chloramphenicol
chromium
female hormones, like estrogens or progestins and birth control pills
fluoxetine
heart medicines like disopyramide
isoniazid
male hormones or anabolic steroids
medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl
medicines for allergies, asthma, cold, or cough
medicines for mental problems
medicines for weight loss
niacin
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
pentamidine
phenytoin
probenecid
quinolone antibiotics like ciprofloxacin, levofloxacin, ofloxacin
some herbal dietary supplements
steroid medicines like prednisone or cortisone
thyroid medicine
water pills or diuretics

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.

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Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.

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