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Generic Name: paliperidone

An atypical antipsychotic - It is used to treat schizophrenia and schizoaffective disorder

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What is this medicine?

PALIPERIDONE (pal ee PER i done) is used to treat schizophrenia and schizoaffective disorder.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

chronic constipation or diarrhea
dementia
diabetes or family history of diabetes
history of stroke
irregular heartbeat or low blood pressure
kidney disease
liver disease
stomach problems like adhesions, bowel disease, short gut, trouble swallowing
an unusual or allergic reaction to paliperidone, risperidone, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not chew, crush, or cut tablets. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your prescriber's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

bepridil
cisapride
droperidol
grepafloxacin
halofantrine
levomethadyl
pimozide
sertindole
some phenothiazines like chlorpromazine, mesoridazine, thioridazine
sparfloxacin

This medicine may also interact with the following medications:

abarelix
alcohol
alfuzosin
antibiotics like clarithromycin, erythromycin, gemifloxacin, levofloxacin
chloroquine
cyclobenzaprine
daunorubicin, doxorubicin
dolasetron
levodopa and other medications for Parkinson's disease
lithium
local anesthetics
medicines for anxiety, depression or psychotic disturbances
medicines for blood pressure
medicines for irregular heartbeat
medicines for sleep
medicines for treating seizures
octreotide
ondansetron
other medicines for schizophrenia
pentamidine
prescription pain medications
tramadol
vorinostat

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects. Do not suddenly stop taking this medicine. You may need to gradually reduce the dose. Only stop taking this medicine on the advice of your doctor or health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Avoid extreme heat. This medicine can cause you to sweat less than normal. Your body temperature could increase to dangerous levels, which may lead to heat stroke.

The tablet shell for some brands of this medicine does not dissolve. This is normal. The tablet shell may appear whole in the stool. This is not a cause for concern.

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Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.

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