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A baby that is born prematurely often has a low birth weight, but not always. A baby may be premature and be normal weight or full-term and be low birth weight.
Table 1 below shows the number of babies born in the U.S. in 1997, according to the baby's gestational age. (Gestational age refers to the number of weeks a woman is pregnant. It is usually calculated from the first day of the last normal menstrual period.)
|Weeks Gestation||Number of Births||Percent of Total Live Births|
|Less than 28 weeks||28,005||0.7%|
|42 weeks or greater||302,541||7.8|
Note: This table is adapted from Anderson's Delivery of the Preterm Infant.
Premature babies often have medical problems because their organs and body systems have not developed sufficiently. The lungs, brain, gastrointestinal tract, and immune system are most often affected and pose the greatest risks for causing long-term problems and death (see the tables below). To some degree, all organs and body systems are immature and may cause complications in the premature baby.
|Birth Weight:||501-750 gms|
| Complication: |
Gestational age (weeks)
|Respiratory distress syndrome||71%||54%||36%||22%|
|Moderate bleeding in the brain (Grade 3)||12%||9%||6%||4%|
|Severe bleeding in the brain (Grade 4)||13%||5%||3%||1%|
|Chronic lung disease||47%||33%||15%||6%|
|Inflammation or death of part of the GI tract (necrotizing enterocolitis, or NEC)||11%||9%||6%||3%|
|Survival to 120 days or hospital discharge||56%||88%||94%||96%|
|Survival without any of these complications||36%||59%||79%||90%|
Note: Table contains data from the National Institute of Child Health and Human Development, Neonatal Research Network for 1997-2000, adapted from Avery's Diseases of the Newborn, 8th Edition.
Because of these problems of prematurity, many babies who are born too small or too early need special care in a neonatal intensive care unit (NICU). As might be expected, the smaller or more premature a baby is, the more likely it is to need special care. For example, babies with very low birth weight make up the majority of babies in the NICU. Babies with extremely low birth weights, however, make up a much smaller number of the babies in the NICU but they stay longer-as a group, they account for 40% of the days spent per year in the average NICU.
The NICU has made a big difference in the outcomes of premature and low birth weight babies. Twenty years ago, most babies who weighed between 500 and 1,000 grams (1 pound, 2 ounces and 2 pounds, 3 ounces, respectively) at birth would survive only a few hours to a few days. At present, the majority of these babies survive, but they may be in the NICU for 30 to 90 days, depending on their birth weight.
Written by: the Healthline Editorial Team
Medically reviewed : Mandy Belfort, Department of Neonatal-Perinatal Medicine, Children's Hospital Boston, Boston, MA
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