Get exclusive member benefits & effect social change. Join Today
For congestive heart failure, high-quality trials have used doses of 60 milligrams three times per day or 80 milligrams twice a day for products containing standardized extract WS 1442 (18.75% oligomeric procyanidines). The U.S. brand HeartCare® (Nature's Way) is standardized in this fashion.
Other high-quality trials have used doses of 100 milligrams three times per day, 200 milligrams twice a day, and up to 300 milligrams three times a day for products containing standardized extract LI 132 (2.2% flavonoids).
The dosage range recommended in review literature is 160-900 milligrams hawthorn extract per day in 2-3 divided doses (corresponding to 3.5-19.8 milligrams flavonoids or 30-168.8 milligrams oligomeric procyanidines). Some sources recommend a range of 240-480 milligrams per day for extracts standardized to 18.75% oligomeric procyanidines.
Not enough available scientific evidence.
Avoid if allergic to hawthorn or to members of the Crataegus genus. There is a case report of an immediate-type hypersensitivity reaction to hawthorn plants. It is not known if this applies to formulations taken by mouth.
There are limited reports of adverse effects associated with hawthorn. Numerous human trials, observational studies including over 4,500 patients, and case reports have noted rare adverse effects, including abdominal discomfort, nausea, agitation, dizziness, headache, fatigue, shortness of breath, skin rash, insomnia, sweating, and rapid heart rate.
Not recommended due to lack of sufficient data.
Additive inotropic effects when used with cardiac glycoside drugs such as digoxin have been noted in animals without added toxicity. In humans, hawthorn has been used with the intention of decreasing digoxin doses, although data on safe and efficacious dosing in this setting is still limited.
Hawthorn may have additive activity with medications that lower blood pressure. Hawthorn may add to the activity of drugs that dilate blood vessels, and may decrease the effects of vasoconstrictors such as phenylephrine (Neo-Synephrine®), ephedrine or norepinephrine. Hawthorn may interact with cholesterol-lowering agents.
Hawthorn may add to the effects on the heart of agents containing cardiac glycosides, such as foxglove (Digitalis purpurea).
Hawthorn may add to the effects of agents that lower blood pressure, and may also interact with agents that increase blood pressure.
Enter your symptoms in our Symptom Checker to find out possible causes of your symptoms. Go.
Enter any list of prescription drugs and see how they interact with each other and with other substances. Go.
Enter its color and shape information, and this tool helps you identify it. Go.
From companies that meet the high standards of service and quality set by AARP.
Members can print savings coupons at the Grocery Coupon Center powered by Coupons.com.
Members can find discounts on the go via the AARP® Member Advantages Offer Finder mobile app.
Go Digital with RealPad. Connect, play and share plus free 24/7 live customer support.
Join or renew today! AARP members receive exclusive member benefits & affect social change.
Register at a location near you to keep your driving skills sharp.
Find opportunities to volunteer in your neighborhood.
NASCAR champ Jeff Gordon teams up with AARP Foundation.