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Generic Name: acetaminophen/pseudoephedrine

It is used to treat symptoms of the common cold and other sinus congestion with pain or fever
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Tylenol Sinus, Sinutab Regular Strength, Sudogest Sinus Maximum Strength, Sudafed Sinus, Contac Sinus, Allerest No Drowsiness, Dristan Cold Non-Drowsy, Bayer Select Decongestant, Max Strength Daytime Sinus Caplets, Genapap Sinus, Non-Aspirin Sinus, Sinarest Sinus, Sinus Relief, Nexafed Sinus And Pain, Tavist Sinus, Contac, Bayer Select Sinus Pain Formula, Tylenol Sinus Maximum Strength, Mapap Sinus, Sudafed Sinus Headache, Pseudoephedrine Sinus, Tylenol Sinus Childrens, Phenapap, Benadryl Allergy Sinus Headache, Non-Drowsy Sinus Maximum Strength, Ornex Maximum Strength, Tylenol Cold Infants, Sinus Maximum Strength, Excedrin Sinus, Suphedrin Plus, Sine-off Maximum Strength, Allerest, Ornex, Sinutab, Tylenol Sinus Gelcap, Sudafed Cold And Sinus, Suphedrin Sinus, Ephed Plus Cold Flu And Sinus, Sinutab Maximum Strength, Theraflu Sinus, Alka-seltzer Cold And Sinus, Sinutab Maximum Strength Non Drowsy, Triaminic Softchews Allergy Sinus

What is this medicine?

ACETAMINOPHEN; PSEUDOEPHEDRINE (a set a MEE noe fen; soo doe e FED rin) is a combination of a pain reliever and a decongestant. It is used to treat symptoms of the common cold and other sinus congestion with pain or fever.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • glaucoma
  • heart disease
  • high blood pressure
  • if you frequently drink alcohol containing drinks
  • kidney disease
  • liver disease
  • prostate trouble
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • thyroid disease
  • trouble passing urine
  • an unusual or allergic reaction to acetaminophen, pseudoephedrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the package or prescription label. Do not chew, crush, or cut. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • bromocriptine
  • ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • acetaminophen
  • alcohol
  • atropine
  • bretylium
  • caffeine
  • digoxin
  • isoniazid
  • linezolid
  • mecamylamine
  • medicines for blood pressure
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for enlarged prostate
  • medicines for sleep
  • other medicines for cold, cough or allergy
  • procarbazine
  • reserpine
  • St. John's Wort

What should I watch for while using this medicine?

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. Check with your doctor if you have a fever for more than 3 days or if your congestion lasts more than 7 days. Get medical help if you have a sore throat for more than 2 days or if you have a sore throat with fever, headache, rash, swelling, nausea, or vomiting.

If you have difficulty sleeping at night while using this medicine, take your last dose a few hours before bedtime. If nervousness, dizziness, or sleeplessness occur, stop using and consult a health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.

If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.

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All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.
Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.
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