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Generic Name: allopurinol

Too much uric acid in the blood can cause damage to your kidneys
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What is this medicine?

ALLOPURINOL (al oh PURE i nole) reduces the amount of uric acid the body makes during chemotherapy. Too much uric acid in the blood can cause damage to your kidneys.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • kidney disease
  • liver disease
  • an unusual or allergic reaction to allopurinol, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast feeding

How should I use this medicine?

The medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with the following medication:
  • didanosine, ddI

This medicine may also interact with the following medications:

  • amoxicillin or ampicillin
  • azathioprine
  • certain medicines used to treat gout
  • chlorpropamide
  • cyclosporine
  • diuretics
  • mercaptopurine
  • probenecid
  • sulfinpyrazone
  • warfarin

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Drink plenty of water while you are taking this medicine. This will help to reduce the risk of getting gout or kidney stones.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • difficulty passing urine
  • loss of appetite
  • redness, blistering, peeling or loosening of the skin, including inside the mouth
  • unusual bleeding or bruising
  • unusually weak or tired
  • vomiting
  • yellowing of the skin or whites of the eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • drowsiness
  • nausea
  • stomach pain

Where should I keep my medicine?

This drug is given in a hospital or clinic and will not be stored at home.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.
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Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.
 
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