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Generic Name: bismuth subsalicylate/metronidazole/tcn

It is used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection
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What is this medicine?

BISMUTH SUBSALICYLATE; METRONIDAZOLE; TETRACYCLINE (biz muth sub sa LIS i late; me troe NI da zole; tet ra SYE kleen) is a combination antibiotic. It is used to treat stomach ulcers associated with Helicobacter pylori, a bacterial infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • kidney disease
  • liver disease
  • nerve problems like neuropathy
  • recent vaccination with chickenpox vaccine
  • recent viral illness, such as the flu or chickenpox
  • seizures
  • an unusual or allergic reaction to bismuth subsalicylate, metronidazole, tetracycline, aspirin or other salicylates, or other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Do not take it with milk or other dairy products. Follow the directions on the prescription label. This medicine should be taken after meals and at bedtime. Do not take your medicine more often than directed. Take all of your medicine as directed even if you think you are better. Do not skip doses or stop your medicine early.

Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you miss more than 4 doses, contact your doctor or health care professional.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • alcohol or any product that contains alcohol
  • disulfiram
  • medicines for HIV
  • methotrexate
  • other antibiotics like tetracyclines, sulfamethoxazole; trimethoprim
  • sertraline

This medicine may also interact with the following medications:

  • antacids with aluminum, calcium, magnesium, sodium bicarbonate
  • aspirin and aspirin-like drugs
  • birth control pills
  • calcium supplements
  • cimetidine
  • iron supplements
  • lithium
  • magnesium supplements
  • medicines for diabetes
  • medicines that treat or prevent blood clots like warfarin
  • methoxyflurane
  • penicillin
  • phenobarbital
  • phenytoin
  • probenecid
  • sulfinpyrazone
  • zinc supplements or zinc lozenges

What should I watch for while using this medicine?

Visit your doctor for regular check ups. Tell your doctor if your symptoms do not get better or if they get worse.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

Avoid products with aluminum, calcium, magnesium, iron, zinc, or sodium bicarbonate for 2 hours before and after taking a dose of this medicine.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Do not drink alcohol while you are taking this medicine and for at least 1 day after finishing treatment.

This medicine may cause dark tongue and/or grayish black stools. This is only temporary and will go away when you stop taking this medicine.

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All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.
Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.
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