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Generic Name: dextromethorphan/guaifenesin/phenylephrine

It is used to treat cough and congestion
View All Brands
Execof Er, Robitussin Pediatric Cough & Cold Cf, Duravent Dm, Tusso-Xr, Gfn 1200/Dm 20/Pe 40, Dexcon-Pe, Tussex, Robitussin Children'S Cough & Cold Cf, Neotuss Improved, Dacex-Pe, Trituss-Er, Genetuss 2, Robitussin Peak Cold Maximum Strength Multi-Symptom Cold, Wal-Tussin Cf, Robitussin Peak Cold Multi-Symptom Cold, Zotex, Robitussin Cough & Cold Cf, Mucinex Fast-Max Severe Congestion And Cough, Ambi 40/1000/60, Tusso-Dm, Dacex-Dm, Guaphen Ii Dm, Duraphen Forte, Despec Eda, Deconex Dm, Despec Dm Reformulated Sep 2008, Zotex Lax, Z-Dex, Tusso-Dmr, Trituss, G-Phen Dm, Despec Dm, Tussi-Pres, Phlemex Forte, Tussafed-Ex Drops, Giltuss Tr, Vanacof Dm, Maxiphen Dm Reformulated Jul 2008, Broncotron-D Reformulated Dec 2012, Pdm Gg, Phlemex-Pe, Guaphen Forte, Despec Dm Syrup, Q-Tussin Cf, Maxiphen Dm, Robafen Cf Reformulated Feb 2008, Giltuss, Anextuss, Duraphen Dm, Deconex Dmx, Sinutuss Dm, Execof, Broncotron Ped, Endacon, Mucinex Multi-Symptom Cold Children'S, Tussafed-Ex, Tusicof, Duraphen Ii Dm, Endacon Dm, Certuss-D, Exetuss-Dm, Duramax, Gdp-Ex, Robafen Cf, Z-Tuss Dm, Dexcon-Dm, Maxiphen-G Dm

What is this medicine?

DEXTROMETHORPHAN; GUAIFENESIN; PHENYLEPHRINE (dex troe meth OR fan; gwye FEN e sin; fen il EF rin) is a combination of a cough suppressant, an expectorant, and a decongestant. It is used to treat cough and congestion. This medicine will not treat an infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:
  • diabetes
  • enlarged prostrate
  • glaucoma
  • heart disease
  • high blood pressure
  • if you have taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days
  • lung or breathing disease, like asthma
  • thyroid disease
  • an unusual or allergic reaction to dextromethorphan, guaifenesin, phenylephrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take with food or milk. Use a specially marked spoon or container to measure your dose. Household spoons are not accurate. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for selected conditions, precautions do apply.

Patients over 60 years old may have a stronger reaction and need a smaller dose.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • ergot alkaloids like dihydroergotamine
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • stimulant medicines for attention disorders, weight loss, or to stay awake

This medicine may also interact with the following medications:

  • alcohol
  • barbiturates like phenobarbital
  • certain heart medicines like metoprolol, digoxin, and methyldopa
  • diuretics
  • doxazosin
  • medicines for depression, anxiety, or psychotic disturbances
  • medicines for sleep
  • medicines to treat blood pressure
  • muscle relaxers
  • other medicines for cold, cough, or allergy
  • some medicines used for sleep during surgery
  • tamsulosin

What should I watch for while using this medicine?

Talk to your doctor if your cough lasts for more than 1 week. If you have a high fever, skin rash, lasting headache, or sore throat, see your doctor.

Drink several glasses of water each day. This will help loosen mucus.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • anxiety, irritable, or excited
  • breathing problems
  • confusion
  • fast, irregular heartbeat
  • seizures
  • tremor
  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea
  • dizziness
  • headache
  • nausea, vomiting
  • stomach upset
  • tiredness
  • trouble sleeping

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All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.
Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.
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