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Brand Name: Sitrex

Generic Name: guaifenesin/phenylephrine

It is used to provide relief from cough and congestion
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Sinuvent Pe, Triaminic Chest & Nasal Congestion, Baczol Expectorant, Mucinex Stuffy Nose & Cold, Amitex La, Zyrphen, Guaifenesin-Phenylephrine Hydrochloride, Amidal, Duraphen 1000, Despec Reformulated Jun 2008, Nazarin, Duratuss, Nariz, Gfn 800/Pe 25, Aldex, D-Phen 1000, Refenesen Pe, Maxiphen Reformulated Jul 2008, Gilphex Tr, Prolex Pd, Mucinex Children'S Cold, Nexphen Pd, Crantex La Tablets, Prolex D, Xedec, Nasex-G, Lusair, Rescon-gg, Sudex, Duraphen Ii, Crantex Er, Phenavent La, Respa-Pe, Medent-Pei, Donatussin Drops, Exetuss-Gp, Xpect-pe, Gfn 1200/Phenylephrine 40, Maxiphen, Crantex, Visonex, Exetuss, Mucus Relief Sinus, Guiadex Pd, Sina-12x, Liquibid-d, Aldex G, Phenavent Ped, Zotex Gpx, Deconsal Pediatric, Extendryl G, Montephen, Mydex, Genexa La, Endal, Quindal, Nescon-Pd, Guaiphen-D 600, Liquibid-pd, Aquatab D Dose Pack, Sudafed Pe Non-drying Sinus, Liquibid Pdr, D-Tab, Gilphex, J-max, Lusonex, Deconex Ir, Sitrex Pd, Entex La, Fenesin Pe Ir, Duratuss (obsolete), Guaifed Caps, Nasex, Tussbid, Pe-Guai, Duravent Pe, Gfn 600/Phenylephrine 20, Guiatex Pe, Liquibid Dr, Medent-Pe, Simuc, Reluri, Ambi 40/1000, Phenavent, Sinupan, Deconsal Ii, Crantex La Capsules, Norel Ex, Simuc-Gp, Efasin, Xedec Ii, Liquibid-D 1200, Pendex, Wellbid-D 1200, Duratuss Pe, Duratuss Gp, Phenavent D, Sitrex, Despec, Guaiphen-Pd, Entex Lq, Deconex, Duomax, Guaiphen-D 1200, Dynex La, Robitussin Head & Chest Congestion, Guaifen Pe, Wellbid-d, Gfn 600/Phenylephrine 40, Entex Er, Gentex La, Chemdal

What is this medicine?

GUAIFENESIN; PHENYLEPHRINE (gwye FEN e sin; fen il EF rin) is a decongestant, expectorant combination. It is used to provide relief from cough and congestion. This medicine will not treat an infection.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of the following conditions:
  • blood vessel disease
  • diabetes
  • fever
  • glaucoma
  • heart disease or heart rhythm problems
  • high blood pressure
  • other chronic disease
  • prostate trouble
  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate within the last 14 days
  • thyroid disease
  • an unusual or allergic reaction to guaifenesin, phenylephrine, other medicines, foods, dyes, or preservatives
  • pregnant or trying to get pregnant
  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. Take with food or milk. Do not crush or chew. Take your doses at regular times. Do not take more medicine than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years old for selected conditions, precautions do apply.

Patients over 60 years old may have a stronger reaction to this medicine and need smaller doses.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:
  • any stimulant medication
  • bromocriptine
  • ergot medications for headaches or some procedures
  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
  • procarbazine

This medicine may also interact with the following medications:

  • indomethacin
  • mecamylamine
  • medicines for chest pain, heart disease, high blood pressure, or heart rhythm problems
  • medicines for depression or other mental disturbances
  • methyldopa
  • other medicines for allergies or colds
  • reserpine
  • some medicines used during surgery

What should I watch for while using this medicine?

Tell your doctor or health care professional if your symptoms do not improve within 5 days or if they get worse. If you have trouble falling asleep at night, take the last dose of the day at least a few hours before bedtime.

Drink 6 to 8 glasses water daily while you are taking this medicine to help loosen mucus.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:
  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
  • confusion
  • difficulty passing urine
  • fast or irregular heartbeat
  • hallucinations
  • high blood pressure
  • seizure
  • tremor
  • trouble breathing

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • anxiety, excitement, irritability, nervousness
  • diarrhea
  • dizziness
  • headache
  • loss of appetite
  • stomach upset, nausea

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

All visitors to AARP.org should seek expert medical care and consult their own physicians for any specific health issues. Read this disclaimer in its entirety.
Note: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have question about the drug(s) you are taking, check with your health care professional.
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