Get exclusive member benefits & effect social change. Join Today
Mitral valve disease refers to irregular conditions of the mitral valve. This valve is located between the two left chambers of your heart. It works to keep blood flowing properly in one direction from the left atrium to the left ventricle and prevents it from flowing backward.
When your mitral valve does not work properly, you can experience symptoms such as fatigue and shortness of breath because the defective valve is allowing blood to flow backward into the left atrium. Many people with mitral valve disease experience no symptoms.
When the mitral valve does not function as it should, your heart does not pump enough blood out of the left ventricular chamber to supply your body with oxygen-filled blood. Mitral valve disease can be serious. Left untreated, severe cases can lead to heart failure or irregular heartbeats, called arrhythmias, which may be life-threatening.
There are three types of mitral valve disease: stenosis, prolapse, and regurgitation.
The valve opening becomes narrow. This means that not enough blood can pass through into your left ventricle.
The flaps on the valve bulge instead of closing tightly. This might prevent the valve from closing completely, and regurgitation — the backward flow of blood — may occur.
Blood leaks from the valve and flows backward into your left atrium when the left ventricle compresses.
Each form of mitral valve disease has its own set of causes.
Mitral valve stenosis is typically caused by scarring from rheumatic fever. Usually a childhood disease, rheumatic fever results from the body’s immune response to a streptococcal bacterial infection. Rheumatic fever is a serious complication of strep throat or scarlet fever.
The organs most affected by acute rheumatic fever are the joints and the heart. The joints can become inflamed, which can lead to temporary and sometimes chronic disability. Various parts of the heart can become inflamed and lead to these potentially serious heart conditions:
If the mitral valve becomes inflamed or otherwise injured by these conditions, it can lead to the chronic heart condition called rheumatic heart disease. The clinical signs and symptoms of this condition might not occur until 5 to 10 years after the episode of rheumatic fever.
Mitral stenosis is uncommon in the United States and other developed countries where rheumatic fever is rare. This is because people in developed countries generally have access to antibiotics that treat bacterial infections such as strep throat, according to the Merck Manual Home Health Handbook. Most cases of mitral stenosis in the United States are in older adults who had rheumatic fever before the widespread use of antibiotics or in people who have moved from countries where rheumatic fever is common.
There are other causes of mitral valve stenosis, but these are rare. They include:
Mitral valve prolapse often has no specific or known cause. It tends to run in families or occur in those who have other conditions, such as scoliosis and connective tissue problems, which can contribute to mitral valve prolapse. According to the American Heart Association, about 2 percent of the U.S. population has a mitral valve prolapse. Even fewer people experience serious problems associated with the condition.
A variety of heart problems can cause mitral valve regurgitation. You may develop mitral valve regurgitation if you’ve had:
Damage to your heart’s tissue cords or wear and tear to your mitral valve can also lead to regurgitation. Mitral valve prolapse can sometimes cause regurgitation.
Mitral valve disease symptoms vary depending on the exact problem with your valve. A problem with your mitral valve may cause no symptoms at all. When symptoms do occur, they can include:
You may also feel pain or tightness in your chest. In some cases, you might feel your heart beating irregularly or quickly.
Symptoms of any type of mitral valve disease usually develop gradually. Symptoms might appear or get worse when your body is dealing with some sort of extra stress, such as infection or pregnancy.
If your doctor suspects that you may have a mitral valve disease, they will listen to your heart with a stethoscope. Unusual sounds or rhythm patterns can help them diagnose what’s going on.
Other tests that may help confirm a mitral valve disease diagnosis include:
Your doctor may want to monitor you while you exercise to determine how your heart responds to physical stress.
Treatment for mitral valve disease may not be necessary, depending on the severity of your condition and symptoms. If your case is severe enough, there are three possible treatments or combination of treatments that may correct your condition.
If treatment is necessary, your doctor may begin by treating you with medications. There are no medications that can actually fix the structural issues with your mitral valve. Some medications can ease your symptoms or prevent them from getting worse. These medications may include:
In some cases, your doctor may need to perform medical procedures. For example, in cases of mitral valve stenosis, your doctor may be able to use a balloon to open up the valve in a procedure called balloon valvuloplasty.
Surgery may become necessary. Your doctor might be able to surgically repair your existing mitral valve to make it function properly. If that isn’t possible, you may need to have your mitral valve replaced with a new one. The replacement might be either biological or mechanical. The biological replacement might be obtained from a cow, pig, or human cadaver.
When the mitral valve does not function as it should, your blood does not flow properly out of the heart. You may experience symptoms such as fatigue or shortness of breath, or you may not experience symptoms at all. Your doctor will use a variety of tests to diagnose your condition. Treatment usually involves a variety of medications, medical procedures, or surgery.
Written by: Gretchen Holm
Medically reviewed on: Sep 19, 2016: Debra Sullivan, PhD, MSN, CNE, COI
Enter your symptoms in our Symptom Checker to find out possible causes of your symptoms. Go.
Enter any list of prescription drugs and see how they interact with each other and with other substances. Go.
Enter its color and shape information, and this tool helps you identify it. Go.
Find information on drug interactions, side effects, and more. Go.